| Dataset | RNR_GSEA_DESEQ2_FC |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | V$FOXO3_01 |
| Enrichment Score (ES) | 0.16732542 |
| Normalized Enrichment Score (NES) | 2.9665124 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.3289036E-4 |
| FWER p-Value | 0.001 |

| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IL21 | 19 | 5.157 | 0.0033 | Yes | ||
| 2 | CACNG2 | 152 | 1.815 | 0.0005 | Yes | ||
| 3 | NRG1 | 173 | 1.634 | 0.0037 | Yes | ||
| 4 | DLX2 | 176 | 1.628 | 0.0079 | Yes | ||
| 5 | NDST4 | 196 | 1.537 | 0.0112 | Yes | ||
| 6 | NRN1L | 345 | 1.112 | 0.0075 | Yes | ||
| 7 | BDNF | 380 | 1.046 | 0.0100 | Yes | ||
| 8 | UPK1B | 394 | 1.025 | 0.0136 | Yes | ||
| 9 | OMD | 591 | 0.777 | 0.0073 | Yes | ||
| 10 | CLC | 608 | 0.757 | 0.0107 | Yes | ||
| 11 | GTF2A1L | 660 | 0.717 | 0.0123 | Yes | ||
| 12 | IRF4 | 749 | 0.641 | 0.0118 | Yes | ||
| 13 | AQP2 | 770 | 0.628 | 0.0151 | Yes | ||
| 14 | PDK4 | 823 | 0.611 | 0.0166 | Yes | ||
| 15 | FOXP2 | 943 | 0.550 | 0.0144 | Yes | ||
| 16 | TMEM71 | 1001 | 0.517 | 0.0157 | Yes | ||
| 17 | HOXB8 | 1101 | 0.482 | 0.0146 | Yes | ||
| 18 | MAFF | 1142 | 0.458 | 0.0168 | Yes | ||
| 19 | COL8A1 | 1227 | 0.433 | 0.0165 | Yes | ||
| 20 | PDZRN4 | 1275 | 0.415 | 0.0183 | Yes | ||
| 21 | GFRA1 | 1287 | 0.408 | 0.0221 | Yes | ||
| 22 | ETV5 | 1310 | 0.401 | 0.0252 | Yes | ||
| 23 | PRDM1 | 1351 | 0.387 | 0.0273 | Yes | ||
| 24 | CNTF | 1363 | 0.382 | 0.0311 | Yes | ||
| 25 | KIF20A | 1377 | 0.379 | 0.0347 | Yes | ||
| 26 | CPVL | 1533 | 0.344 | 0.0306 | Yes | ||
| 27 | DDIT4 | 1630 | 0.322 | 0.0297 | Yes | ||
| 28 | OTX2 | 1672 | 0.316 | 0.0318 | Yes | ||
| 29 | SEMA3A | 1760 | 0.300 | 0.0314 | Yes | ||
| 30 | SEPP1 | 1777 | 0.296 | 0.0349 | Yes | ||
| 31 | C1QTNF7 | 1783 | 0.295 | 0.0389 | Yes | ||
| 32 | UTY | 1921 | 0.271 | 0.0358 | Yes | ||
| 33 | HMCN1 | 1954 | 0.267 | 0.0384 | Yes | ||
| 34 | DLL1 | 2047 | 0.256 | 0.0377 | Yes | ||
| 35 | PSMA8 | 2073 | 0.254 | 0.0407 | Yes | ||
| 36 | COLEC10 | 2099 | 0.251 | 0.0437 | Yes | ||
| 37 | DIXDC1 | 2130 | 0.247 | 0.0464 | Yes | ||
| 38 | IKZF2 | 2184 | 0.241 | 0.0478 | Yes | ||
| 39 | PDE7A | 2201 | 0.238 | 0.0513 | Yes | ||
| 40 | ZMAT4 | 2283 | 0.230 | 0.0512 | Yes | ||
| 41 | CDK11A | 2367 | 0.221 | 0.0510 | Yes | ||
| 42 | PELI2 | 2526 | 0.208 | 0.0468 | Yes | ||
| 43 | JMJD1C | 2530 | 0.208 | 0.0509 | Yes | ||
| 44 | RGAG1 | 2557 | 0.205 | 0.0538 | Yes | ||
| 45 | ID2 | 2578 | 0.204 | 0.0571 | Yes | ||
| 46 | FAM134B | 2610 | 0.201 | 0.0597 | Yes | ||
| 47 | CHD6 | 2624 | 0.200 | 0.0634 | Yes | ||
| 48 | CDK14 | 2899 | 0.179 | 0.0528 | Yes | ||
| 49 | SREK1 | 3026 | 0.171 | 0.0503 | Yes | ||
| 50 | MBNL2 | 3069 | 0.169 | 0.0523 | Yes | ||
| 51 | RBP2 | 3114 | 0.166 | 0.0543 | Yes | ||
| 52 | PLAG1 | 3131 | 0.165 | 0.0577 | Yes | ||
| 53 | RSF1 | 3143 | 0.164 | 0.0614 | Yes | ||
| 54 | NEDD4 | 3165 | 0.162 | 0.0646 | Yes | ||
| 55 | ASTN1 | 3166 | 0.161 | 0.0690 | Yes | ||
| 56 | TAL1 | 3202 | 0.160 | 0.0714 | Yes | ||
| 57 | CSRNP3 | 3284 | 0.156 | 0.0713 | Yes | ||
| 58 | PHLPP1 | 3332 | 0.154 | 0.0731 | Yes | ||
| 59 | FRY | 3339 | 0.153 | 0.0771 | Yes | ||
| 60 | UBE2H | 3382 | 0.152 | 0.0791 | Yes | ||
| 61 | LCP2 | 3424 | 0.149 | 0.0812 | Yes | ||
| 62 | PURA | 3473 | 0.147 | 0.0830 | Yes | ||
| 63 | DOCK4 | 3513 | 0.145 | 0.0852 | Yes | ||
| 64 | PPP1CB | 3537 | 0.143 | 0.0883 | Yes | ||
| 65 | TJP1 | 3551 | 0.143 | 0.0919 | Yes | ||
| 66 | ZEB2 | 3554 | 0.143 | 0.0961 | Yes | ||
| 67 | WHSC1L1 | 3616 | 0.139 | 0.0971 | Yes | ||
| 68 | HS3ST1 | 3622 | 0.139 | 0.1012 | Yes | ||
| 69 | HBP1 | 3693 | 0.136 | 0.1017 | Yes | ||
| 70 | KLF12 | 3731 | 0.134 | 0.1040 | Yes | ||
| 71 | CFL2 | 3802 | 0.131 | 0.1045 | Yes | ||
| 72 | BRAF | 3837 | 0.129 | 0.1070 | Yes | ||
| 73 | ZNF277 | 3884 | 0.127 | 0.1088 | Yes | ||
| 74 | NR3C2 | 3932 | 0.125 | 0.1106 | Yes | ||
| 75 | TIGD4 | 4015 | 0.122 | 0.1105 | Yes | ||
| 76 | KDM6A | 4039 | 0.121 | 0.1136 | Yes | ||
| 77 | TNRC6A | 4073 | 0.119 | 0.1161 | Yes | ||
| 78 | NUB1 | 4078 | 0.119 | 0.1202 | Yes | ||
| 79 | RARB | 4111 | 0.118 | 0.1228 | Yes | ||
| 80 | PKN2 | 4128 | 0.118 | 0.1263 | Yes | ||
| 81 | UBR5 | 4135 | 0.117 | 0.1303 | Yes | ||
| 82 | ZFAND2A | 4251 | 0.113 | 0.1283 | Yes | ||
| 83 | SLITRK6 | 4349 | 0.110 | 0.1274 | Yes | ||
| 84 | CITED2 | 4393 | 0.108 | 0.1294 | Yes | ||
| 85 | PCDH18 | 4482 | 0.105 | 0.1289 | Yes | ||
| 86 | TTC33 | 4493 | 0.105 | 0.1327 | Yes | ||
| 87 | SNCAIP | 4533 | 0.104 | 0.1349 | Yes | ||
| 88 | FGF12 | 4665 | 0.099 | 0.1321 | Yes | ||
| 89 | ICK | 4684 | 0.098 | 0.1355 | Yes | ||
| 90 | CACNA2D1 | 4832 | 0.093 | 0.1318 | Yes | ||
| 91 | SH3RF1 | 4837 | 0.093 | 0.1360 | Yes | ||
| 92 | LIX1L | 5013 | 0.088 | 0.1308 | Yes | ||
| 93 | LRP5 | 5074 | 0.087 | 0.1318 | Yes | ||
| 94 | ARID4A | 5075 | 0.087 | 0.1362 | Yes | ||
| 95 | RAD54B | 5135 | 0.085 | 0.1373 | Yes | ||
| 96 | CHD2 | 5153 | 0.085 | 0.1407 | Yes | ||
| 97 | MAPK10 | 5273 | 0.081 | 0.1386 | Yes | ||
| 98 | ENPP2 | 5374 | 0.079 | 0.1374 | Yes | ||
| 99 | CREBL2 | 5513 | 0.075 | 0.1343 | Yes | ||
| 100 | IKZF4 | 5562 | 0.074 | 0.1360 | Yes | ||
| 101 | PTCH1 | 5569 | 0.073 | 0.1400 | Yes | ||
| 102 | CDKN1C | 5627 | 0.072 | 0.1412 | Yes | ||
| 103 | NFIB | 5801 | 0.067 | 0.1362 | Yes | ||
| 104 | FAM105A | 5812 | 0.067 | 0.1399 | Yes | ||
| 105 | STC2 | 5873 | 0.065 | 0.1410 | Yes | ||
| 106 | ATF2 | 5945 | 0.063 | 0.1415 | Yes | ||
| 107 | CXorf23 | 5947 | 0.063 | 0.1458 | Yes | ||
| 108 | STARD13 | 5963 | 0.063 | 0.1493 | Yes | ||
| 109 | PHTF2 | 6000 | 0.062 | 0.1516 | Yes | ||
| 110 | MBNL1 | 6126 | 0.059 | 0.1492 | Yes | ||
| 111 | PRKAG1 | 6144 | 0.059 | 0.1526 | Yes | ||
| 112 | SERINC3 | 6147 | 0.059 | 0.1568 | Yes | ||
| 113 | PRKCI | 6173 | 0.058 | 0.1598 | Yes | ||
| 114 | SMAD5 | 6187 | 0.058 | 0.1634 | Yes | ||
| 115 | FBXO9 | 6226 | 0.057 | 0.1657 | Yes | ||
| 116 | TPP1 | 6379 | 0.053 | 0.1617 | Yes | ||
| 117 | CIR1 | 6420 | 0.052 | 0.1639 | Yes | ||
| 118 | TBL1X | 6499 | 0.050 | 0.1640 | Yes | ||
| 119 | PHF15 | 6518 | 0.050 | 0.1673 | Yes | ||
| 120 | CNNM3 | 6673 | 0.047 | 0.1633 | No | ||
| 121 | NNAT | 6765 | 0.045 | 0.1627 | No | ||
| 122 | ULK1 | 6926 | 0.041 | 0.1583 | No | ||
| 123 | PHF21A | 6970 | 0.040 | 0.1603 | No | ||
| 124 | EZH1 | 7001 | 0.040 | 0.1630 | No | ||
| 125 | TEX2 | 7143 | 0.036 | 0.1597 | No | ||
| 126 | MPP6 | 7391 | 0.031 | 0.1506 | No | ||
| 127 | CDK11B | 7456 | 0.030 | 0.1514 | No | ||
| 128 | CHCHD7 | 7534 | 0.028 | 0.1516 | No | ||
| 129 | LDB2 | 7578 | 0.027 | 0.1536 | No | ||
| 130 | MEIS2 | 7582 | 0.027 | 0.1577 | No | ||
| 131 | GTF2B | 7606 | 0.027 | 0.1608 | No | ||
| 132 | POLR2L | 7731 | 0.024 | 0.1584 | No | ||
| 133 | ARFIP1 | 7889 | 0.021 | 0.1542 | No | ||
| 134 | CADM1 | 7927 | 0.021 | 0.1565 | No | ||
| 135 | WIPI2 | 8172 | 0.016 | 0.1476 | No | ||
| 136 | EFNA1 | 8402 | 0.011 | 0.1395 | No | ||
| 137 | LMO3 | 8462 | 0.010 | 0.1406 | No | ||
| 138 | RFX3 | 8484 | 0.009 | 0.1438 | No | ||
| 139 | CLPX | 8760 | 0.004 | 0.1331 | No | ||
| 140 | BUB3 | 8957 | 0.000 | 0.1268 | No | ||
| 141 | HIBADH | 8969 | -0.000 | 0.1306 | No | ||
| 142 | SRSF7 | 9007 | -0.001 | 0.1329 | No | ||
| 143 | NXN | 9076 | -0.003 | 0.1335 | No | ||
| 144 | VPS26A | 9080 | -0.003 | 0.1377 | No | ||
| 145 | DIEXF | 9112 | -0.003 | 0.1403 | No | ||
| 146 | ZADH2 | 9329 | -0.008 | 0.1329 | No | ||
| 147 | BRD8 | 9452 | -0.010 | 0.1306 | No | ||
| 148 | FGF9 | 9685 | -0.015 | 0.1223 | No | ||
| 149 | ZNF362 | 9822 | -0.017 | 0.1193 | No | ||
| 150 | PDCD4 | 10048 | -0.021 | 0.1114 | No | ||
| 151 | BCL7A | 10057 | -0.022 | 0.1153 | No | ||
| 152 | TXNDC12 | 10066 | -0.022 | 0.1191 | No | ||
| 153 | TBC1D17 | 10095 | -0.022 | 0.1220 | No | ||
| 154 | SHOX2 | 10098 | -0.022 | 0.1262 | No | ||
| 155 | ABTB1 | 10145 | -0.023 | 0.1280 | No | ||
| 156 | FOXO1 | 10147 | -0.023 | 0.1323 | No | ||
| 157 | TRIM63 | 10226 | -0.024 | 0.1324 | No | ||
| 158 | SUMO1 | 10247 | -0.025 | 0.1356 | No | ||
| 159 | NFIX | 10312 | -0.026 | 0.1365 | No | ||
| 160 | RXRB | 10377 | -0.027 | 0.1373 | No | ||
| 161 | DTNA | 10405 | -0.028 | 0.1402 | No | ||
| 162 | TRPC4 | 10435 | -0.029 | 0.1429 | No | ||
| 163 | AKIRIN2 | 10727 | -0.035 | 0.1314 | No | ||
| 164 | CLIP2 | 10884 | -0.039 | 0.1273 | No | ||
| 165 | TGFB3 | 11101 | -0.044 | 0.1199 | No | ||
| 166 | NRAS | 11153 | -0.045 | 0.1214 | No | ||
| 167 | IL1RAPL1 | 11269 | -0.048 | 0.1195 | No | ||
| 168 | TSPAN4 | 11302 | -0.049 | 0.1221 | No | ||
| 169 | ACACA | 11313 | -0.049 | 0.1259 | No | ||
| 170 | MCM7 | 11334 | -0.050 | 0.1291 | No | ||
| 171 | IMPDH2 | 11402 | -0.051 | 0.1298 | No | ||
| 172 | ZNF521 | 11520 | -0.054 | 0.1278 | No | ||
| 173 | SCRN3 | 12006 | -0.065 | 0.1058 | No | ||
| 174 | SALL3 | 12045 | -0.066 | 0.1080 | No | ||
| 175 | SH2D4A | 12146 | -0.068 | 0.1069 | No | ||
| 176 | SQSTM1 | 12290 | -0.072 | 0.1035 | No | ||
| 177 | WDR46 | 12617 | -0.081 | 0.0901 | No | ||
| 178 | SLC39A7 | 12660 | -0.082 | 0.0921 | No | ||
| 179 | NXPH3 | 12844 | -0.088 | 0.0865 | No | ||
| 180 | PDGFRB | 12884 | -0.089 | 0.0887 | No | ||
| 181 | KITLG | 12904 | -0.089 | 0.0920 | No | ||
| 182 | AP4M1 | 13046 | -0.093 | 0.0887 | No | ||
| 183 | FUZ | 13142 | -0.096 | 0.0879 | No | ||
| 184 | ZBTB22 | 13194 | -0.098 | 0.0894 | No | ||
| 185 | PFDN6 | 13415 | -0.105 | 0.0818 | No | ||
| 186 | NTRK3 | 13453 | -0.106 | 0.0841 | No | ||
| 187 | AP1G2 | 13559 | -0.110 | 0.0827 | No | ||
| 188 | PTCHD1 | 13684 | -0.115 | 0.0803 | No | ||
| 189 | RBFOX1 | 13934 | -0.125 | 0.0711 | No | ||
| 190 | PAX6 | 13970 | -0.126 | 0.0735 | No | ||
| 191 | BMI1 | 14034 | -0.130 | 0.0744 | No | ||
| 192 | AKT1S1 | 14040 | -0.130 | 0.0785 | No | ||
| 193 | GRB7 | 14386 | -0.148 | 0.0641 | No | ||
| 194 | CTLA4 | 14426 | -0.150 | 0.0663 | No | ||
| 195 | BIN1 | 14469 | -0.152 | 0.0683 | No | ||
| 196 | FBXL22 | 14659 | -0.162 | 0.0624 | No | ||
| 197 | HLX | 14763 | -0.168 | 0.0611 | No | ||
| 198 | SKAP1 | 14968 | -0.183 | 0.0544 | No | ||
| 199 | TRIM8 | 15267 | -0.206 | 0.0425 | No | ||
| 200 | NTN1 | 15303 | -0.210 | 0.0449 | No | ||
| 201 | JUNB | 15515 | -0.230 | 0.0378 | No | ||
| 202 | TSPAN33 | 15624 | -0.240 | 0.0363 | No | ||
| 203 | ITGA3 | 15638 | -0.242 | 0.0399 | No | ||
| 204 | VSIG2 | 15765 | -0.258 | 0.0374 | No | ||
| 205 | HR | 15777 | -0.260 | 0.0411 | No | ||
| 206 | SOX12 | 15844 | -0.269 | 0.0418 | No | ||
| 207 | FOXD3 | 15877 | -0.272 | 0.0444 | No | ||
| 208 | NMNAT2 | 15913 | -0.277 | 0.0468 | No | ||
| 209 | LAG3 | 16099 | -0.300 | 0.0411 | No | ||
| 210 | TFAP4 | 16260 | -0.328 | 0.0368 | No | ||
| 211 | PMCH | 16290 | -0.332 | 0.0395 | No | ||
| 212 | TTR | 16340 | -0.341 | 0.0412 | No | ||
| 213 | FOXB1 | 16435 | -0.361 | 0.0404 | No | ||
| 214 | C12orf50 | 16499 | -0.377 | 0.0413 | No | ||
| 215 | PITX2 | 16527 | -0.383 | 0.0442 | No | ||
| 216 | MRGPRF | 16592 | -0.398 | 0.0450 | No | ||
| 217 | BCL11B | 16598 | -0.399 | 0.0491 | No | ||
| 218 | CRH | 16671 | -0.418 | 0.0495 | No | ||
| 219 | EGR2 | 16810 | -0.456 | 0.0463 | No | ||
| 220 | SYT6 | 16816 | -0.458 | 0.0504 | No | ||
| 221 | LHX9 | 16882 | -0.475 | 0.0512 | No | ||
| 222 | NR1D1 | 17106 | -0.538 | 0.0434 | No | ||
| 223 | HAS2 | 17361 | -0.660 | 0.0339 | No | ||
| 224 | GFI1B | 17405 | -0.681 | 0.0359 | No | ||
| 225 | C5orf64 | 17475 | -0.720 | 0.0365 | No | ||
| 226 | EFCAB3 | 17576 | -0.783 | 0.0354 | No | ||
| 227 | ELOVL6 | 17680 | -0.868 | 0.0341 | No | ||
| 228 | TBX4 | 17769 | -0.939 | 0.0336 | No | ||
| 229 | STOML3 | 17903 | -1.042 | 0.0307 | No | ||
| 230 | POU3F4 | 18403 | -1.983 | 0.0080 | No | ||
| 231 | NKX2-1 | 18557 | -4.263 | 0.0040 | No |
